Indication | Drug | Adult Dose | Duration |
---|---|---|---|
Primary prophylaxis |
Ganciclovir (If CMV prophylaxis indicated) |
1 g PO three times a day |
First 3 months post transplant |
Valganciclovir (If CMV prophylaxis indicated) |
900 mg PO once a day |
||
Acyclovir |
600-1000 mg/day (over 3-5 doses) |
First 6 months post transplant (if not on CMV prophylaxis) |
|
Valacyclovir |
500 mg PO twice a day |
||
Secondary prophylaxis |
VariZIG |
125 units/10 kg IM once (625 units maximum, 125 units minimum) |
Within 96 hours of exposure |
IVIG |
400 mg/kg IV once |
After 96 hours of exposure |
|
Acyclovir |
800 mg PO Four times a day |
For 7 days, starting on day 7-10 post exposure |
|
Valacyclovir |
1g PO three times a day |